74 research outputs found

    Confirmatory Factor Analysis using Amos, LISREL, Mplus, SAS/STAT CALIS

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    Factor analysis is a statistical method used to find a small set of unobserved variables (also called latent variables, or factors) which can account for the covariance among a larger set of observed variables (also called manifest variables). A factor is an unobservable variable that is assumed to influence observed variables. Scores on multiple tests may be indicators of intelligence (Spearman, 1904); political liberties and popular sovereignty may measure the quality of a country’s democracy (Bollen, 1980); or issue emphases in election manifestos may signify a political party’s underlying ideology (Gabel & Huber, 2000). Factor analysis is also used to assess the reliability and validity of measurement scales (Carmines & Zeller, 1979)

    Defining Success for Students with Autism Spectrum Disorder: Social Academic Behavior in General Education Secondary Classes

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    An exploratory, observation-based study sought to strengthen understanding of the development of social communication skills that facilitate academic success, particularly within general education settings. Sixteen middle and high school students with Autism Spectrum Disorders (ASD), all of whom participated in at least one period per day of core academic instruction in a general education classroom, were observed over a period of one to three months each. Frequencies of five appropriate and three inappropriate social academic behaviors are described, in terms of their relative frequencies to one another, and their overall consistency over the course of observations. Students observed were more likely to engage in appropriate, facilitative behaviors within the classroom setting than they were to demonstrate communicative symptoms of ASD. Most social academic behaviors were demonstrated at consistent frequencies over time. Implications for educational decision-making, progress monitoring, and future research are discussed

    No Consensus on Definition Criteria for Stroke Registry Common Data Elements

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    www.karger.com/cee This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License (www.karger.com/OA-license), applicable to the online version of the article only. Distribution for non-commercial purposes only

    Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

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    Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio

    What Makes Retirees Happier: A Gradual or 'Cold Turkey' Retirement?

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    This study explores the factors that affect an individual’s happiness while transitioning into retirement. Recent studies highlight gradual retirement as an attractive option to older workers as they approach full retirement. However, it is not clear whether phasing or cold turkey makes for a happier retirement. Using longitudinal data from the Health and Retirement Study, this study explores what shapes the change in happiness between the last wave of full employment and the first wave of full retirement. Results suggest that what really matters is not the type of transition (gradual retirement or cold turkey), but whether people perceive the transition as chosen or forced

    Does the number of parties to place affect the placement of parties? Results from an expert survey experiment

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    Expert surveys are frequently used in comparative politics to measure the ideological locations of political parties. However, it is possible that increasing the number of parties to place systematically biases results as experts try to fit more actors onto a common space. We test this possibility with an experiment embedded in an “expert” survey – with graduate students serving as our pool of experts to ensure an adequate sample size – by varying the number of parties to be placed in the United Kingdom and Germany. We find some tendency for the variance of Labour and SPD placements to diminish when more parties are present, and for SPD placements to move toward the center given more parties. However, we find no consistent evidence that the number of parties systematically affects mean or median party placements. Our results support the reliability of expert surveys as an indicator of party ideology
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